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Assessment of intratumoral heterogeneity with mutations and gene expression profiles
Intratumoral heterogeneity (ITH) refers to the presence of distinct tumor cell populations. It provides vital information for the clinical prognosis, drug responsiveness, and personalized treatment of cancer patients. As genomic ITH in various cancers affects the expression patterns of genes, the ex...
Autores principales: | Sung, Ji-Yong, Shin, Hyun-Tae, Sohn, Kyung-Ah, Shin, Soo-Yong, Park, Woong-Yang, Joung, Je-Gun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634409/ https://www.ncbi.nlm.nih.gov/pubmed/31310640 http://dx.doi.org/10.1371/journal.pone.0219682 |
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