Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene

While many disease-associated single nucleotide polymorphisms (SNPs) are associated with gene expression (expression quantitative trait loci, eQTLs), a large proportion of complex disease genome-wide association study (GWAS) variants are of unknown function. Some of these SNPs may contribute to dise...

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Detalles Bibliográficos
Autores principales: Saferali, Aabida, Yun, Jeong H., Parker, Margaret M., Sakornsakolpat, Phuwanat, Chase, Robert P., Lamb, Andrew, Hobbs, Brian D., Boezen, Marike H., Dai, Xiangpeng, de Jong, Kim, Beaty, Terri H., Wei, Wenyi, Zhou, Xiaobo, Silverman, Edwin K., Cho, Michael H., Castaldi, Peter J., Hersh, Craig P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634423/
https://www.ncbi.nlm.nih.gov/pubmed/31269066
http://dx.doi.org/10.1371/journal.pgen.1008229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634423/
https://www.ncbi.nlm.nih.gov/pubmed/31269066
http://dx.doi.org/10.1371/journal.pgen.1008229

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