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Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis

To ensure proper segregation during mitosis, chromosomes must be efficiently captured by spindle microtubules and subsequently aligned on the mitotic spindle. The efficacy of chromosome interaction with the spindle can be influenced by how widely chromosomes are scattered in space. Here, we quantify...

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Detalles Bibliográficos
Autores principales: Booth, Alexander JR, Yue, Zuojun, Eykelenboom, John K, Stiff, Tom, Luxton, GW Gant, Hochegger, Helfrid, Tanaka, Tomoyuki U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634967/
https://www.ncbi.nlm.nih.gov/pubmed/31264963
http://dx.doi.org/10.7554/eLife.46902