A role for ABCB1 in prognosis, invasion and drug resistance in ependymoma

Three of the hallmarks of poor prognosis in paediatric ependymoma are drug resistance, local invasion and recurrence. We hypothesised that these hallmarks were due to the presence of a sub-population of cancer stem cells expressing the multi-drug efflux transporter ABCB1. ABCB1 gene expression was o...

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Detalles Bibliográficos
Autores principales: Sabnis, Durgagauri H., Storer, Lisa C. D., Liu, Jo-Fen, Jackson, Hannah K., Kilday, J. P., Grundy, Richard G., Kerr, Ian D., Coyle, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635358/
https://www.ncbi.nlm.nih.gov/pubmed/31311995
http://dx.doi.org/10.1038/s41598-019-46700-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635358/
https://www.ncbi.nlm.nih.gov/pubmed/31311995
http://dx.doi.org/10.1038/s41598-019-46700-z

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