Identification and Characterization of Genetic Determinants of Isoniazid and Rifampicin Resistance in Mycobacterium tuberculosis in Southern India

Drug-resistant tuberculosis (TB), one of the leading causes of death worldwide, arises mainly from spontaneous mutations in the genome of Mycobacterium tuberculosis. There is an urgent need to understand the mechanisms by which the mutations confer resistance in order to identify new drug targets an...

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Detalles Bibliográficos
Autores principales: Munir, Asma, Kumar, Narender, Ramalingam, Suresh Babu, Tamilzhalagan, Sembulingam, Shanmugam, Siva Kumar, Palaniappan, Alangudi Natarajan, Nair, Dina, Priyadarshini, Padma, Natarajan, Mohan, Tripathy, Srikanth, Ranganathan, Uma Devi, Peacock, Sharon J., Parkhill, Julian, Blundell, Tom L., Malhotra, Sony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635374/
https://www.ncbi.nlm.nih.gov/pubmed/31311987
http://dx.doi.org/10.1038/s41598-019-46756-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635374/
https://www.ncbi.nlm.nih.gov/pubmed/31311987
http://dx.doi.org/10.1038/s41598-019-46756-x

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