Acute Iron Deprivation Reprograms Human Macrophage Metabolism and Reduces Inflammation In Vivo

Iron is an essential metal that fine-tunes the innate immune response by regulating macrophage function, but an integrative view of transcriptional and metabolic responses to iron perturbation in macrophages is lacking. Here, we induced acute iron chelation in primary human macrophages and measured...

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Detalles Bibliográficos
Autores principales: Pereira, Marie, Chen, Tai-Di, Buang, Norzawani, Olona, Antoni, Ko, Jeong-Hun, Prendecki, Maria, Costa, Ana S.H., Nikitopoulou, Efterpi, Tronci, Laura, Pusey, Charles D., Cook, H. Terence, McAdoo, Stephen P., Frezza, Christian, Behmoaras, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635384/
https://www.ncbi.nlm.nih.gov/pubmed/31291584
http://dx.doi.org/10.1016/j.celrep.2019.06.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635384/
https://www.ncbi.nlm.nih.gov/pubmed/31291584
http://dx.doi.org/10.1016/j.celrep.2019.06.039

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