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Three-Dimensional Genomic Structure and Cohesin Occupancy Correlate with Transcriptional Activity during Spermatogenesis

Mammalian gametogenesis involves dramatic and tightly regulated chromatin remodeling, whose regulatory pathways remain largely unexplored. Here, we generate a comprehensive high-resolution structural and functional atlas of mouse spermatogenesis by combining in situ chromosome conformation capture s...

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Detalles Bibliográficos
Autores principales: Vara, Covadonga, Paytuví-Gallart, Andreu, Cuartero, Yasmina, Le Dily, François, Garcia, Francisca, Salvà-Castro, Judit, Gómez-H, Laura, Julià, Eva, Moutinho, Catia, Aiese Cigliano, Riccardo, Sanseverino, Walter, Fornas, Oscar, Pendás, Alberto M., Heyn, Holger, Waters, Paul D., Marti-Renom, Marc A., Ruiz-Herrera, Aurora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635386/
https://www.ncbi.nlm.nih.gov/pubmed/31291573
http://dx.doi.org/10.1016/j.celrep.2019.06.037