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Cerebellar disruption impairs working memory during evidence accumulation

To select actions based on sensory evidence, animals must create and manipulate representations of stimulus information in memory. Here we report that during accumulation of somatosensory evidence, optogenetic manipulation of cerebellar Purkinje cells reduces the accuracy of subsequent memory-guided...

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Detalles Bibliográficos
Autores principales: Deverett, Ben, Kislin, Mikhail, Tank, David W., Wang, Samuel S.-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635393/
https://www.ncbi.nlm.nih.gov/pubmed/31311934
http://dx.doi.org/10.1038/s41467-019-11050-x