HDAC6 depletion improves cystic fibrosis mouse airway responses to bacterial challenge

The hypothesis of this study was that Hdac6 depletion would restore cystic fibrosis (CF) responses to bacterial challenge to more wild type profiles using a CF mouse model. CF mice harboring the F508del Cftr mutation respond to bacterial challenge with 25,000 CFU Pseudomonas aeruginosa embedded into...

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Detalles Bibliográficos
Autores principales: Rosenjack, Julie, Hodges, Craig A., Darrah, Rebecca J., Kelley, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635416/
https://www.ncbi.nlm.nih.gov/pubmed/31311988
http://dx.doi.org/10.1038/s41598-019-46555-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635416/
https://www.ncbi.nlm.nih.gov/pubmed/31311988
http://dx.doi.org/10.1038/s41598-019-46555-4

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