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Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome

Pulmonary surfactant protein A (SP-A) plays an important role in surfactant metabolism and lung innate immunity. In humans there are two proteins, SP-A1 and SP-A2, encoded by SFTPA1 and SFTPA2, respectively, which are produced by the alveolar type II cells (T2C). We sought to investigate the differe...

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Detalles Bibliográficos
Autores principales: Noutsios, George T., Thorenoor, Nithyananda, Zhang, Xuesheng, Phelps, David S., Umstead, Todd M., Durrani, Faryal, Floros, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635478/
https://www.ncbi.nlm.nih.gov/pubmed/31354704
http://dx.doi.org/10.3389/fimmu.2019.01514