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Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay

Obesity is associated with ~40% of cancer diagnoses but there are currently no effective preventive strategies, illustrating a need for chemoprevention. We previously demonstrated that fibroblast growth factor 2 (FGF2) from adipose tissue stimulates malignant transformation, as measured by growth in...

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Detalles Bibliográficos
Autores principales: Benham, Vanessa, Bullard, Blair, Dexheimer, Thomas S., Bernard, Matthew P., Neubig, Richard R., Liby, Karen T., Bernard, Jamie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635484/
https://www.ncbi.nlm.nih.gov/pubmed/31311976
http://dx.doi.org/10.1038/s41598-019-46531-y