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Zebrafish preserve global germline DNA methylation while sex-linked rDNA is amplified and demethylated during feminisation
The germline is the only cellular lineage capable of transferring genetic information from one generation to the next. Intergenerational transmission of epigenetic memory through the germline, in the form of DNA methylation, has been proposed; however, in mammals this is largely prevented by extensi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635516/ https://www.ncbi.nlm.nih.gov/pubmed/31311924 http://dx.doi.org/10.1038/s41467-019-10894-7 |