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Zebrafish preserve global germline DNA methylation while sex-linked rDNA is amplified and demethylated during feminisation

The germline is the only cellular lineage capable of transferring genetic information from one generation to the next. Intergenerational transmission of epigenetic memory through the germline, in the form of DNA methylation, has been proposed; however, in mammals this is largely prevented by extensi...

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Detalles Bibliográficos
Autores principales: Ortega-Recalde, Oscar, Day, Robert C., Gemmell, Neil J., Hore, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635516/
https://www.ncbi.nlm.nih.gov/pubmed/31311924
http://dx.doi.org/10.1038/s41467-019-10894-7