HnRNPA1 interacts with G-quadruplex in the TRA2B promoter and stimulates its transcription in human colon cancer cells

The human TRA2B gene consists of 10 exons and 9 introns and produces 5 splice isoforms (TRA2β1 to TRA2β5). TRA2B exon 2 encodes multiple premature termination codons. TRA2β1 lacks exon 2 and is translated into a functional transformer 2β (Tra2β) protein, whereas TRA2β4 contains 10 exons and works as...

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Detalles Bibliográficos
Autores principales: Nishikawa, Tatsuya, Kuwano, Yuki, Takahara, Yumiko, Nishida, Kensei, Rokutan, Kazuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635519/
https://www.ncbi.nlm.nih.gov/pubmed/31311954
http://dx.doi.org/10.1038/s41598-019-46659-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635519/
https://www.ncbi.nlm.nih.gov/pubmed/31311954
http://dx.doi.org/10.1038/s41598-019-46659-x

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