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Clinical Persistence of Chlamydia trachomatis Sexually Transmitted Strains Involves Novel Mutations in the Functional αββα Tetramer of the Tryptophan Synthase Operon

Clinical persistence of Chlamydia trachomatis (Ct) sexually transmitted infections (STIs) is a major public health concern. In vitro persistence is known to develop through interferon gamma (IFN-γ) induction of indoleamine 2,3-dioxygenase (IDO), which catabolizes tryptophan, an essential amino acid...

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Detalles Bibliográficos
Autores principales: Somboonna, Naraporn, Ziklo, Noa, Ferrin, Thomas E., Hyuk Suh, Jung, Dean, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635532/
https://www.ncbi.nlm.nih.gov/pubmed/31311884
http://dx.doi.org/10.1128/mBio.01464-19