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P2X7-mediated ATP secretion is accompanied by depletion of cytosolic ATP

ATP and its metabolites are important extracellular signal transmitters acting on purinergic P2 and P1 receptors. Most cells can actively secrete ATP in response to a variety of external stimuli such as gating of the P2X7 receptor. We used Yac-1 murine lymphoma cells to study P2X7-mediated ATP relea...

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Detalles Bibliográficos
Autores principales: Johnsen, Bjarne, Kaschubowski, Klaus Eric, Nader, Sorush, Schneider, Enja, Nicola, Jan-Andrei, Fliegert, Ralf, Wolf, Insa M. A., Guse, Andreas H., Nikolaev, Viacheslav O., Koch-Nolte, Friedrich, Haag, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635544/
https://www.ncbi.nlm.nih.gov/pubmed/31016551
http://dx.doi.org/10.1007/s11302-019-09654-5