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Development, Optimization, and Validation of a High Throughput Screening Assay for Identification of Tat and Type II Secretion Inhibitors of Pseudomonas aeruginosa

Antibiotics are becoming less effective in treatment of infections caused by multidrug-resistant Pseudomonas aeruginosa. Antimicrobial therapies based on the inhibition of specific virulence-related traits, as opposed to growth inhibitors, constitute an innovative and appealing approach to tackle th...

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Detalles Bibliográficos
Autores principales: Massai, Francesco, Saleeb, Michael, Doruk, Tugrul, Elofsson, Mikael, Forsberg, Åke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635566/
https://www.ncbi.nlm.nih.gov/pubmed/31355152
http://dx.doi.org/10.3389/fcimb.2019.00250