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Fully-automated radiosynthesis of the amyloid tracer [(11)C] PiB via direct [(11)C]CO(2) fixation-reduction
BACKGROUND: The β-amyloid radiotracer [(11)C] PiB is extensively used for the Positron Emission Tomography (PET) diagnosis of Alzheimer’s Disease and related dementias. For clinical use, [(11)C] PiB is produced using the (11)C-methylation method ([(11)C] Methyl iodide or [(11)C] methyl triflate as (...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635575/ https://www.ncbi.nlm.nih.gov/pubmed/31659494 http://dx.doi.org/10.1186/s41181-019-0065-4 |