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Synergistic Enhancement of Paclitaxel-induced Inhibition of Cell Growth by Metformin in Melanoma Cells

Melanoma is one of the most aggressive and treatment-resistant malignancies. Antidiabetic drug metformin has been reported to inhibit cell proliferation and metastasis in many cancers, including melanoma. Metformin suppresses the mammalian target of rapamycin (mTOR) and our previous study showed tha...

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Detalles Bibliográficos
Autores principales: Ko, Gihyun, Kim, Taehyung, Ko, Eunjeong, Park, Deokbae, Lee, Youngki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Developmental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635613/
https://www.ncbi.nlm.nih.gov/pubmed/31321352
http://dx.doi.org/10.12717/DR.2019.23.2.119