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Hfq Globally Binds and Destabilizes sRNAs and mRNAs in Yersinia pestis

Hfq is a ubiquitous Sm-like RNA-binding protein in bacteria involved in physiological fitness and pathogenesis, while its in vivo binding nature remains elusive. Here we reported genome-wide Hfq-bound RNAs in Yersinia pestis, a causative agent of plague, by using cross-linking immunoprecipitation co...

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Detalles Bibliográficos
Autores principales: Han, Yanping, Chen, Dong, Yan, Yanfeng, Gao, Xiaofang, Liu, Zizhong, Xue, Yaqiang, Zhang, Yi, Yang, Ruifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635623/
https://www.ncbi.nlm.nih.gov/pubmed/31311844
http://dx.doi.org/10.1128/mSystems.00245-19