The Impact of Carboxylesterases in Drug Metabolism and Pharmacokinetics

Background: Carboxylesterases (CES) play a critical role in catalyzing hydrolysis of esters, amides, carbamates and thioesters, as well as bioconverting prodrugs and soft drugs. The unique tissue distribution of CES enzymes provides great opportunities to design prodrugs or soft drugs for tissue tar...

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Detalles Bibliográficos
Autor principal: Di, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635651/
https://www.ncbi.nlm.nih.gov/pubmed/30129408
http://dx.doi.org/10.2174/1389200219666180821094502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635651/
https://www.ncbi.nlm.nih.gov/pubmed/30129408
http://dx.doi.org/10.2174/1389200219666180821094502

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