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Cancer‐associated fibroblasts show heterogeneous gene expression and induce vascular endothelial growth factor A (VEGFA) in response to environmental stimuli

AIM: Cancer‐associated fibroblasts (CAF) play a crucial role in angiogenesis in the complex tumor microenvironment. However, fibroblasts show extensive heterogeneity and their dynamic functions against stressors remain largely unknown. METHODS: We collected patient‐derived CAF and carried out pertur...

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Detalles Bibliográficos
Autores principales: Inoue, Ken‐ichi, Kishimoto, Satoko, Akimoto, Kazumi, Sakuma, Masashi, Toyoda, Shigeru, Inoue, Teruo, Yoshida, Ken‐ichiro, Shimoda, Mitsugi, Suzuki, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635680/
https://www.ncbi.nlm.nih.gov/pubmed/31346581
http://dx.doi.org/10.1002/ags3.12249