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Deoxynivalenol enhances IL-1ß expression in BV2 microglial cells through activation of the NF-?B pathway and the ASC/NLRP3 inflammasome

Deoxynivalenol (DON) is one of the most common fungal toxins that contaminate food grains and cereal-derived products. However, it is unknown whether DON stimulates IL-1β expression through the activation of the nuclear factor-κB (NF-κB) pathway and the ACS/NLRP3 inflammasome. In this study, we foun...

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Detalles Bibliográficos
Autores principales: Molagoda, Ilandarage Menu Neelaka, Lee, Seunghun, Jayasooriya, Rajapaksha Gedara Prasad Tharanga, Jin, Cheng-Yung, Choi, Yung Hyun, Kim, Gi-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635726/
https://www.ncbi.nlm.nih.gov/pubmed/31338007
http://dx.doi.org/10.17179/excli2018-1974