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Generation of Foxp3(+)CD25(−) Regulatory T-Cell Precursors Requires c-Rel and IκB(NS)
Next to the classical developmental route, in which first CD25 and subsequently Foxp3 are induced to generate thymic regulatory T (Treg) cells, an alternative route has been described. This alternative route is characterized by reciprocal induction of Foxp3 and CD25, with CD25 induction being requir...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635800/ https://www.ncbi.nlm.nih.gov/pubmed/31354726 http://dx.doi.org/10.3389/fimmu.2019.01583 |