Cargando…
Generation of Foxp3(+)CD25(−) Regulatory T-Cell Precursors Requires c-Rel and IκB(NS)
Next to the classical developmental route, in which first CD25 and subsequently Foxp3 are induced to generate thymic regulatory T (Treg) cells, an alternative route has been described. This alternative route is characterized by reciprocal induction of Foxp3 and CD25, with CD25 induction being requir...
Autores principales: | Schuster, Marc, Plaza-Sirvent, Carlos, Visekruna, Alexander, Huehn, Jochen, Schmitz, Ingo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635800/ https://www.ncbi.nlm.nih.gov/pubmed/31354726 http://dx.doi.org/10.3389/fimmu.2019.01583 |
Ejemplares similares
-
Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3(+) regulatory T cells
por: Luu, Maik, et al.
Publicado: (2017) -
c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells
por: Isomura, Iwao, et al.
Publicado: (2010) -
c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells
por: Isomura, Iwao, et al.
Publicado: (2009) -
Atypical IκB proteins – nuclear modulators of NF-κB signaling
por: Schuster, Marc, et al.
Publicado: (2013) -
The Treg-Specific Demethylated Region Stabilizes Foxp3 Expression Independently of NF-κB Signaling
por: Schreiber, Lisa, et al.
Publicado: (2014)