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Cyfip1 Haploinsufficiency Does Not Alter GABA(A) Receptor δ-Subunit Expression and Tonic Inhibition in Dentate Gyrus PV(+) Interneurons and Granule Cells

Copy number variation (CNV) at chromosomal region 15q11.2 is linked to increased risk of neurodevelopmental disorders including autism and schizophrenia. A significant gene at this locus is cytoplasmic fragile X mental retardation protein (FMRP) interacting protein 1 (CYFIP1). CYFIP1 protein interac...

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Detalles Bibliográficos
Autores principales: Trent, Simon, Hall, Jeremy, Connelly, William M., Errington, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635810/
https://www.ncbi.nlm.nih.gov/pubmed/31209152
http://dx.doi.org/10.1523/ENEURO.0364-18.2019