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Inaccurate secondary structure predictions often indicate protein fold switching

Although most proteins conform to the classical one‐structure/one‐function paradigm, an increasing number of proteins with dual structures and functions have been discovered. In response to cellular stimuli, such proteins undergo structural changes sufficiently dramatic to remodel even their seconda...

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Detalles Bibliográficos
Autores principales: Mishra, Soumya, Looger, Loren L., Porter, Lauren L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635839/
https://www.ncbi.nlm.nih.gov/pubmed/31148305
http://dx.doi.org/10.1002/pro.3664