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Decitabine enhances cytotoxic effect of T cells with an anti-CD19 chimeric antigen receptor in treatment of lymphoma

Background: CD19-directed chimeric antigen receptor (CAR) T cells have substantial benefit in the treatment of patients with B-cell malignancies. However, despite encouraging therapeutic efficiency, there is limited overall response rate when anti-CD19 CAR-T cells are used to treat patients with rel...

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Detalles Bibliográficos
Autores principales: Li, Sujun, Xue, Lei, Wang, Min, Qiang, Ping, Xu, Hui, Zhang, Xuhan, Kang, Wenyao, You, Fengtao, Xu, Hanying, Wang, Yu, Liu, Xin, Yang, Lin, Wang, Xingbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635897/
https://www.ncbi.nlm.nih.gov/pubmed/31372000
http://dx.doi.org/10.2147/OTT.S198567