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Oncogenic effect of PHLDB2 is associated with epithelial–mesenchymal transition and E-cadherin regulation in colorectal cancer

BACKGROUND: Pleckstrin Homology Like Domain Family Member 2 (PHLDB2) is an important protein with a PH-domain for interaction with partners to regulate cell migration. However, the role of PHLDB2 in human cancer metastasis, especially in colon cancer, still remains elusive. METHODS: The RNA-seq and...

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Detalles Bibliográficos
Autores principales: Chen, Geng, Zhou, Tong, Ma, Tantan, Cao, Tingting, Yu, Zhenxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636018/
https://www.ncbi.nlm.nih.gov/pubmed/31346319
http://dx.doi.org/10.1186/s12935-019-0903-1