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GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver illness with a genetically heterogeneous background that can be accompanied by considerable morbidity and attendant health care costs. The pathogenesis and progression of NAFLD is complex with many unanswered questions....

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Detalles Bibliográficos
Autores principales: Namjou, Bahram, Lingren, Todd, Huang, Yongbo, Parameswaran, Sreeja, Cobb, Beth L., Stanaway, Ian B., Connolly, John J., Mentch, Frank D., Benoit, Barbara, Niu, Xinnan, Wei, Wei-Qi, Carroll, Robert J., Pacheco, Jennifer A., Harley, Isaac T. W., Divanovic, Senad, Carrell, David S., Larson, Eric B., Carey, David J., Verma, Shefali, Ritchie, Marylyn D., Gharavi, Ali G., Murphy, Shawn, Williams, Marc S., Crosslin, David R., Jarvik, Gail P., Kullo, Iftikhar J., Hakonarson, Hakon, Li, Rongling, Xanthakos, Stavra A., Harley, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636057/
https://www.ncbi.nlm.nih.gov/pubmed/31311600
http://dx.doi.org/10.1186/s12916-019-1364-z