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Super-enhancers: critical roles and therapeutic targets in hematologic malignancies
Super-enhancers (SEs) in a broad range of human cell types are large clusters of enhancers with aberrant high levels of transcription factor binding, which are central to drive expression of genes in controlling cell identity and stimulating oncogenic transcription. Cancer cells acquire super-enhanc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636097/ https://www.ncbi.nlm.nih.gov/pubmed/31311566 http://dx.doi.org/10.1186/s13045-019-0757-y |