Extensions of ℓ(1) regularization increase detection specificity for cell-type specific parameters in dynamic models

BACKGROUND: Ordinary differential equation systems are frequently utilized to model biological systems and to infer knowledge about underlying properties. For instance, the development of drugs requires the knowledge to which extent malign cells differ from healthy ones to provide a specific treatme...

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Detalles Bibliográficos
Autores principales: Dolejsch, Pascal, Hass, Helge, Timmer, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636101/
https://www.ncbi.nlm.nih.gov/pubmed/31311516
http://dx.doi.org/10.1186/s12859-019-2976-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636101/
https://www.ncbi.nlm.nih.gov/pubmed/31311516
http://dx.doi.org/10.1186/s12859-019-2976-1

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