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Interferon gamma inhibits the differentiation of mouse adult liver and bone marrow hematopoietic stem cells by inhibiting the activation of notch signaling

BACKGROUND: The paradigm of hematopoietic stem and progenitor cells (HSPCs) has become accepted ever since the discovery of adult mouse liver hematopoietic stem cells and their multipotent characteristics that give rise to all blood cells. However, differences between bone marrow (BM) and liver hema...

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Detalles Bibliográficos
Autores principales: Qin, Yuhong, Fang, Keke, Lu, Nan, Hu, Yuan, Tian, Zhigang, Zhang, Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636148/
https://www.ncbi.nlm.nih.gov/pubmed/31311586
http://dx.doi.org/10.1186/s13287-019-1311-0