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RAG1 high expression associated with IKZF1 dysfunction in adult B-cell acute lymphoblastic leukemia

The recombination mediated by recombination activating gene (RAG) is not only the dominant mutational process but also the predominant driver of oncogenic genomic rearrangement in acute lymphoblastic leukemia (ALL). It is further responsible for leukemic clonal evolution. In this study, significant...

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Detalles Bibliográficos
Autores principales: Han, Qi, Ma, Jinlong, Gu, Yan, Song, Huihui, Kapadia, Malika, Kawasawa, Yuka Imamura, Dovat, Sinisa, Song, Chunhua, Ge, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636280/
https://www.ncbi.nlm.nih.gov/pubmed/31333801
http://dx.doi.org/10.7150/jca.33989