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RAG1 high expression associated with IKZF1 dysfunction in adult B-cell acute lymphoblastic leukemia
The recombination mediated by recombination activating gene (RAG) is not only the dominant mutational process but also the predominant driver of oncogenic genomic rearrangement in acute lymphoblastic leukemia (ALL). It is further responsible for leukemic clonal evolution. In this study, significant...
Autores principales: | Han, Qi, Ma, Jinlong, Gu, Yan, Song, Huihui, Kapadia, Malika, Kawasawa, Yuka Imamura, Dovat, Sinisa, Song, Chunhua, Ge, Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636280/ https://www.ncbi.nlm.nih.gov/pubmed/31333801 http://dx.doi.org/10.7150/jca.33989 |
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