Tumor Suppressor LKB1 inhibits both the mRNA Expression and the Amplification of hTERC by the Phosphorylation of YAP in Lung Cancer Cells

Liver kinase B1 (LKB1) is a critical tumor suppressor that is frequently mutated in human cancers. LKB1 has serine/threonine protein kinase activity, which regulates gene expression by phosphorylation of Yes-Associated protein (YAP). The phosphorylation-dependent YAP shuttling is critically importan...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Ling, Wu, Ming-Zhe, Wang, Xu-Bo, Qiu, Xue-Shan, Wang, En-Hua, Wu, Guang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636284/
https://www.ncbi.nlm.nih.gov/pubmed/31333780
http://dx.doi.org/10.7150/jca.33237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636284/
https://www.ncbi.nlm.nih.gov/pubmed/31333780
http://dx.doi.org/10.7150/jca.33237

Ejemplares similares