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Tumor Suppressor LKB1 inhibits both the mRNA Expression and the Amplification of hTERC by the Phosphorylation of YAP in Lung Cancer Cells

Liver kinase B1 (LKB1) is a critical tumor suppressor that is frequently mutated in human cancers. LKB1 has serine/threonine protein kinase activity, which regulates gene expression by phosphorylation of Yes-Associated protein (YAP). The phosphorylation-dependent YAP shuttling is critically importan...

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Detalles Bibliográficos
Autores principales:	He, Ling, Wu, Ming-Zhe, Wang, Xu-Bo, Qiu, Xue-Shan, Wang, En-Hua, Wu, Guang-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636284/ https://www.ncbi.nlm.nih.gov/pubmed/31333780 http://dx.doi.org/10.7150/jca.33237

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