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EMP2 acts as a suppressor of melanoma and is negatively regulated by mTOR-mediated autophagy

Cutaneous melanoma is one of the most common malignant skin tumors and advanced melanoma is usually associated with a poor prognosis. In the current study, we demonstrated the tumor suppressing role of epithelial membrane protein-2 (EMP2) by inducing apoptosis in a A375 human melanoma cell line. Mec...

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Detalles Bibliográficos
Autores principales: Wang, Manyi, Li, Sijia, Zhang, Peng, Wang, Yujia, Wang, Chunting, Bai, Ding, Jiang, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636303/
https://www.ncbi.nlm.nih.gov/pubmed/31333775
http://dx.doi.org/10.7150/jca.30342