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Induction of antigen-specific immune tolerance using biodegradable nanoparticles containing antigen and dexamethasone

PURPOSE: Dexamethasone (Dex) has long been used as a potent immunosuppressive agent in the treatment of inflammatory and autoimmune diseases, despite serious side effects. In the present study, Dex and model antigen ovalbumin (OVA) were encapsulated with poly(lactic-co-glycolic acid) to deliver Dex...

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Detalles Bibliográficos
Autores principales: Kim, Sang-Hyun, Moon, Jun-Hyeok, Jeong, Seong-Un, Jung, Ho-Hyun, Park, Chan-Su, Hwang, Bang Yeon, Lee, Chong-Kil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636315/
https://www.ncbi.nlm.nih.gov/pubmed/31371958
http://dx.doi.org/10.2147/IJN.S210546