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Design, Synthesis, and Biological Evaluation of (E)-N'-((1-Chloro-3,4-Dihydronaphthalen-2-yl)Methylene)Benzohydrazide Derivatives as Anti-prostate Cancer Agents

Prostate Cancer (PCa) is the most frequently diagnosed cancer in men in their late '50s. PCa growth is mainly due to the activation of the androgen receptor by androgens. The treatment for PCa may involve surgery, hormonal therapy, and oral chemotherapeutic drugs. A structural based molecular d...

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Detalles Bibliográficos
Autores principales: Arjun, H. A., Elancheran, Ramakrishnan, Manikandan, N., Lakshmithendral, K., Ramanathan, Muthiah, Bhattacharjee, Atanu, Lokanath, N. K., Kabilan, Senthamaraikannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636335/
https://www.ncbi.nlm.nih.gov/pubmed/31355179
http://dx.doi.org/10.3389/fchem.2019.00474