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Regorafenib Prior to Selective Internal Radiation Therapy Using (90)Y-Resin Microspheres for Refractory Metastatic Colorectal Cancer Liver Metastases: Analysis of Safety, Dosimetry, and Molecular Markers

Background: This Phase II, open-label, study examined the safety of regorafenib followed by selective internal radiation therapy (SIRT) with regorafenib re-initiation in the treatment of metastatic colorectal cancer (mCRC) patients with liver metastases who are not surgical candidates. Methods: Pati...

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Detalles Bibliográficos
Autores principales: Kennedy, Andrew, Shipley, Dianna, Shpak, Max, Blakely, Laura, Hemphill, Brian, Shih, Kent, Lane, Cassie, Zimmerman, Lisa, McKenzie, Andrew, Mainwaring, Mark, Peyton, James D., Zubkus, John, Wright, David, Singh, Jaswinder, Bendell, Johanna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636394/
https://www.ncbi.nlm.nih.gov/pubmed/31355141
http://dx.doi.org/10.3389/fonc.2019.00624