Cargando…

Regorafenib Prior to Selective Internal Radiation Therapy Using (90)Y-Resin Microspheres for Refractory Metastatic Colorectal Cancer Liver Metastases: Analysis of Safety, Dosimetry, and Molecular Markers

Background: This Phase II, open-label, study examined the safety of regorafenib followed by selective internal radiation therapy (SIRT) with regorafenib re-initiation in the treatment of metastatic colorectal cancer (mCRC) patients with liver metastases who are not surgical candidates. Methods: Pati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kennedy, Andrew, Shipley, Dianna, Shpak, Max, Blakely, Laura, Hemphill, Brian, Shih, Kent, Lane, Cassie, Zimmerman, Lisa, McKenzie, Andrew, Mainwaring, Mark, Peyton, James D., Zubkus, John, Wright, David, Singh, Jaswinder, Bendell, Johanna C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636394/ https://www.ncbi.nlm.nih.gov/pubmed/31355141 http://dx.doi.org/10.3389/fonc.2019.00624

Ejemplares similares

Internal dosimetry for radioembolization therapy with Yttrium‐90 microspheres
por: Fallahpoor, Maryam, et al.
Publicado: (2017)

Post-radioembolization yttrium-90 PET/CT - part 2: dose-response and tumor predictive dosimetry for resin microspheres
por: Kao, Yung-Hsiang, et al.
Publicado: (2013)

A Comparison of Techniques for (90)Y PET/CT Image-Based Dosimetry Following Radioembolization with Resin Microspheres
por: Pasciak, Alexander S., et al.
Publicado: (2014)

Post-treatment three-dimensional voxel-based dosimetry after Yttrium-90 resin microsphere radioembolization in HCC
por: Veenstra, Emile B., et al.
Publicado: (2022)

Standardizing SPECT/CT dosimetry following radioembolization with yttrium-90 microspheres
por: Kim, S. Peter, et al.
Publicado: (2021)

Precision dosimetry in yttrium-90 radioembolization through CT imaging of radiopaque microspheres in a rabbit liver model
por: Henry, E. Courtney, et al.
Publicado: (2022)

Comparison of posttherapy (90)Y positron emission tomography/computed tomography dosimetry methods in liver therapy with (90)Y microspheres
por: Knešaurek, Karin
Publicado: (2020)

Yttrium-90 resin microspheres as an adjunct to sorafenib in patients with unresectable hepatocellular carcinoma
por: Mahvash, Armeen, et al.
Publicado: (2016)

The development, commercialization, and clinical context of yttrium-90 radiolabeled resin and glass microspheres
por: Westcott, Mark A., et al.
Publicado: (2016)

Correction: Precision dosimetry in yttrium-90 radioembolization through CT imaging of radiopaque microspheres in a rabbit liver model
por: Henry, E. Courtney, et al.
Publicado: (2023)

Radiation segmentectomy for hepatic malignancies: Indications, devices, dosimetry, procedure, clinical outcomes, and toxicity of yttrium-90 microspheres
por: Jia, Zhongzhi, et al.
Publicado: (2019)

EANM dosimetry committee series on standard operational procedures: a unified methodology for (99m)Tc-MAA pre- and (90)Y peri-therapy dosimetry in liver radioembolization with (90)Y microspheres
por: Chiesa, Carlo, et al.
Publicado: (2021)

Inter-observer variability of (90)Y PET/CT dosimetry in hepatocellular carcinoma after glass microspheres transarterial radioembolization
por: Meyers, Nicolas, et al.
Publicado: (2020)

Pre- and post-treatment image-based dosimetry in (90)Y-microsphere radioembolization using the TOPAS Monte Carlo toolkit
por: Bertolet, Alejandro, et al.
Publicado: (2021)

Role of Resin Microsphere Y90 Dosimetry in Predicting Objective Tumor Response, Survival and Treatment Related Toxicity in Surgically Unresectable Colorectal Liver Metastasis: A Retrospective Single Institution Study
por: Sankhla, Tina, et al.
Publicado: (2021)

Outcomes and Predictors of Toxicity after Selective Internal Radiation Therapy Using Yttrium-90 Resin Microspheres for Unresectable Hepatocellular Carcinoma
por: Gabrielson, Andrew, et al.
Publicado: (2015)

International recommendations for personalised selective internal radiation therapy of primary and metastatic liver diseases with yttrium-90 resin microspheres
por: Levillain, Hugo, et al.
Publicado: (2021)

A Phase II Study with Lead‐In Safety Cohort of 5‐Fluorouracil, Oxaliplatin, and Lapatinib in Combination with Radiation Therapy as Neoadjuvant Treatment for Patients with Localized HER2‐Positive Esophagogastric Adenocarcinomas
por: Shepard, Gregg, et al.
Publicado: (2017)

Comparison of PET/CT and PET/MR imaging and dosimetry of yttrium-90 ((90)Y) in patients with unresectable hepatic tumors who have received intra-arterial radioembolization therapy with (90)Y microspheres
por: Knešaurek, Karin, et al.
Publicado: (2018)

Evaluation of the delivered activity of yttrium-90 resin microspheres using sterile water and 5 % glucose during administration
por: Ahmadzadehfar, Hojjat, et al.
Publicado: (2015)

Assessment of the relative contribution of volume and concentration changes in Yttrium-90 labelled resin microspheres on ionization chamber measurements
por: Forwood, Nicholas, et al.
Publicado: (2017)

The effect of selective internal radiation therapy with yttrium-90 resin microspheres on lung carbon monoxide diffusion capacity
por: Ones, Tunc, et al.
Publicado: (2017)

Radioembolization with (90)Y Resin Microspheres of Neuroendocrine Liver Metastases After Initial Peptide Receptor Radionuclide Therapy
por: Braat, A. J. A. T., et al.
Publicado: (2019)

Multimodal molecular landscape of response to Y90-resin microsphere radioembolization followed by nivolumab for advanced hepatocellular carcinoma
por: Kaya, Neslihan Arife, et al.
Publicado: (2023)

Clinical impact of (99m)Tc-MAA SPECT/CT-based dosimetry in the radioembolization of liver malignancies with (90)Y-loaded microspheres
por: Garin, Etienne, et al.
Publicado: (2015)

Synthesis of acrylic resin and methacrylic resin microspheres by suspension polymerization
por: Yu, Han, et al.
Publicado: (2023)

Liver Metastases in Pancreatic Acinar Cell Carcinoma Treated with Selective Internal Radiation Therapy with Y-90 Resin Microspheres
por: Nasser, Felipe, et al.
Publicado: (2017)

Assessment of radiation sensitivity of unresectable intrahepatic cholangiocarcinoma in a series of patients submitted to radioembolization with yttrium-90 resin microspheres
por: Depalo, Tommaso, et al.
Publicado: (2021)

Combined Yttrium-90 microsphere selective internal radiation therapy and external beam radiotherapy in patients with hepatocellular carcinoma: From clinical aspects to dosimetry
por: Wang, Ti-Hao, et al.
Publicado: (2018)

Comparing voxel-based absorbed dosimetry methods in tumors, liver, lung, and at the liver-lung interface for (90)Y microsphere selective internal radiation therapy
por: Mikell, Justin K, et al.
Publicado: (2015)

Radioembolization of Hepatocellular Carcinoma with (90)Y Glass Microspheres: No Advantage of Voxel Dosimetry with Respect to Mean Dose in Dose–Response Analysis with Two Radiological Methods
por: Romanò, Chiara, et al.
Publicado: (2022)

Phase I study of capecitabine combined with radioembolization using yttrium-90 resin microspheres (SIR-Spheres) in patients with advanced cancer
por: Cohen, S J, et al.
Publicado: (2014)

Recommendations for radioembolisation after liver surgery using yttrium-90 resin microspheres based on a survey of an international expert panel
por: Samim, Morsal, et al.
Publicado: (2017)

Outcome and Safety after 103 Radioembolizations with Yttrium-90 Resin Microspheres in 73 Patients with Unresectable Intrahepatic Cholangiocarcinoma—An Evaluation of Predictors
por: Paprottka, Karolin J., et al.
Publicado: (2021)

Regorafenib-loaded poly (lactide-co-glycolide) microspheres designed to improve transarterial chemoembolization therapy for hepatocellular carcinoma
por: Li, Xiang, et al.
Publicado: (2020)

Analysis of differences between (99m)Tc-MAA SPECT- and (90)Y-microsphere PET-based dosimetry for hepatocellular carcinoma selective internal radiation therapy
por: Kafrouni, Marilyne, et al.
Publicado: (2019)

Multi-centre phase II clinical trial of yttrium-90 resin microspheres alone in unresectable, chemotherapy refractory colorectal liver metastases
por: Cosimelli, M, et al.
Publicado: (2010)

A multicentre comparison of quantitative (90)Y PET/CT for dosimetric purposes after radioembolization with resin microspheres: The QUEST Phantom Study
por: Willowson, Kathy P., et al.
Publicado: (2015)

Effects of Respiratory Motion on Y-90 PET Dosimetry for SIRT
por: Walker, Matthew D., et al.
Publicado: (2022)

Yttrium-90 microsphere induced gastrointestinal tract ulceration
por: South, Christopher D, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_1np2ql4pjlpdeenaurdg6ep9b7