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Polygenic Risk Score for Alzheimer’s Disease Is Associated With Ch4 Volume in Normal Subjects

Alzheimer’s disease (AD) is a common neurodegenerative disease. APOE is the strong genetic risk factor of AD. The existing genome-wide association studies have identified many single nucleotide polymorphisms (SNPs) with minor effects on AD risk and the polygenic risk score (PRS) is presented to comb...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Han, Zhifa, Yang, Yu, Tian, Rui, Zhou, Wenyang, Ren, Peng, Wang, Pingping, Zong, Jian, Hu, Yang, Jiang, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636399/
https://www.ncbi.nlm.nih.gov/pubmed/31354783
http://dx.doi.org/10.3389/fgene.2019.00519