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A Bispecific Antibody-Based Approach for Targeting Mesothelin in Triple Negative Breast Cancer

Triple negative breast cancers (TNBC) remain a major medical challenge due to poor prognosis and limited treatment options. Mesothelin is a glycosyl-phosphatidyl inositol-linked membrane protein with restricted normal expression and high level expression in a large proportion of TNBC, thus qualifyin...

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Detalles Bibliográficos
Autores principales: Del Bano, Joanie, Florès-Florès, Rémy, Josselin, Emmanuelle, Goubard, Armelle, Ganier, Laetitia, Castellano, Rémy, Chames, Patrick, Baty, Daniel, Kerfelec, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636429/
https://www.ncbi.nlm.nih.gov/pubmed/31354732
http://dx.doi.org/10.3389/fimmu.2019.01593