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A Bispecific Antibody-Based Approach for Targeting Mesothelin in Triple Negative Breast Cancer
Triple negative breast cancers (TNBC) remain a major medical challenge due to poor prognosis and limited treatment options. Mesothelin is a glycosyl-phosphatidyl inositol-linked membrane protein with restricted normal expression and high level expression in a large proportion of TNBC, thus qualifyin...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636429/ https://www.ncbi.nlm.nih.gov/pubmed/31354732 http://dx.doi.org/10.3389/fimmu.2019.01593 |