STAT3 Activation in Combination with NF-KappaB Inhibition Induces Tolerogenic Dendritic Cells with High Therapeutic Potential to Attenuate Collagen-Induced Arthritis

Dendritic cells (DCs) have the ability to induce tolerance or inflammation in response to self-antigens, which makes them fundamental players in autoimmunity. In this regard, immunogenic DCs produce IL-12 and IL-23 favouring the acquisition of Th1 and Th17 inflammatory phenotypes, respectively, by a...

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Detalles Bibliográficos
Autores principales: Prado, Carolina, Ugalde, Valentina, González, Hugo, Figueroa, Alicia, López, Ernesto, Lladser, Alvaro, Pacheco, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636450/
https://www.ncbi.nlm.nih.gov/pubmed/31355296
http://dx.doi.org/10.1155/2019/1982570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636450/
https://www.ncbi.nlm.nih.gov/pubmed/31355296
http://dx.doi.org/10.1155/2019/1982570

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