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Plasticity of Drug-Naïve and Vemurafenib- or Trametinib-Resistant Melanoma Cells in Execution of Differentiation/Pigmentation Program

Melanoma plasticity creates a plethora of opportunities for cancer cells to escape treatment. Thus, therapies must target all cancer cell subpopulations bearing the potential to contribute to disease. The role of the differentiation/pigmentation program in intrinsic and acquired drug resistance is l...

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Detalles Bibliográficos
Autores principales: Czyz, Malgorzata, Sztiller-Sikorska, Malgorzata, Gajos-Michniewicz, Anna, Osrodek, Marta, Hartman, Mariusz L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636509/
https://www.ncbi.nlm.nih.gov/pubmed/31354817
http://dx.doi.org/10.1155/2019/1697913