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Plasticity of Drug-Naïve and Vemurafenib- or Trametinib-Resistant Melanoma Cells in Execution of Differentiation/Pigmentation Program
Melanoma plasticity creates a plethora of opportunities for cancer cells to escape treatment. Thus, therapies must target all cancer cell subpopulations bearing the potential to contribute to disease. The role of the differentiation/pigmentation program in intrinsic and acquired drug resistance is l...
Autores principales: | Czyz, Malgorzata, Sztiller-Sikorska, Malgorzata, Gajos-Michniewicz, Anna, Osrodek, Marta, Hartman, Mariusz L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636509/ https://www.ncbi.nlm.nih.gov/pubmed/31354817 http://dx.doi.org/10.1155/2019/1697913 |
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