Activation of β2-Adrenoceptor Attenuates Sepsis-Induced Hippocampus-Dependent Cognitive Impairments by Reversing Neuroinflammation and Synaptic Abnormalities

Sepsis-associated encephalopathy induces cognitive dysfunction via mechanisms that commonly involve neuroinflammation and synaptic plasticity impairment of the hippocampus. The β2-adrenoceptor (β2-AR) is a G-protein coupled receptor that regulates immune response and synaptic plasticity, whereas its...

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Detalles Bibliográficos
Autores principales: Zong, Man-Man, Zhou, Zhi-Qiang, Ji, Mu-Huo, Jia, Min, Tang, Hui, Yang, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636546/
https://www.ncbi.nlm.nih.gov/pubmed/31354429
http://dx.doi.org/10.3389/fncel.2019.00293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636546/
https://www.ncbi.nlm.nih.gov/pubmed/31354429
http://dx.doi.org/10.3389/fncel.2019.00293

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