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Activation of β2-Adrenoceptor Attenuates Sepsis-Induced Hippocampus-Dependent Cognitive Impairments by Reversing Neuroinflammation and Synaptic Abnormalities

Sepsis-associated encephalopathy induces cognitive dysfunction via mechanisms that commonly involve neuroinflammation and synaptic plasticity impairment of the hippocampus. The β2-adrenoceptor (β2-AR) is a G-protein coupled receptor that regulates immune response and synaptic plasticity, whereas its...

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Detalles Bibliográficos
Autores principales:	Zong, Man-Man, Zhou, Zhi-Qiang, Ji, Mu-Huo, Jia, Min, Tang, Hui, Yang, Jian-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636546/ https://www.ncbi.nlm.nih.gov/pubmed/31354429 http://dx.doi.org/10.3389/fncel.2019.00293

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