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DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway

Esophageal cancer (ESC) is one of the most deadly diseases for human. p53 in most cancers, including ESC cell, is mutated, and the mutated p53 losses its original function and acquires “gain of function” that allows for promoting the hallmarks of cancer, such as antiapoptosis, metastasis, invasion,...

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Detalles Bibliográficos
Autores principales: Wang, Zhuo, Li, Cuiping, Li, Yongli, Guo, Xingshuang, Yan, Zhaoyu, Gao, Fulian, Li, Changzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636558/
https://www.ncbi.nlm.nih.gov/pubmed/31354907
http://dx.doi.org/10.1155/2019/5414670