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Disease gene prediction for molecularly uncharacterized diseases

Network medicine approaches have been largely successful at increasing our knowledge of molecularly characterized diseases. Given a set of disease genes associated with a disease, neighbourhood-based methods and random walkers exploit the interactome allowing the prediction of further genes for that...

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Detalles Bibliográficos
Autores principales: Cáceres, Juan J., Paccanaro, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636748/
https://www.ncbi.nlm.nih.gov/pubmed/31276496
http://dx.doi.org/10.1371/journal.pcbi.1007078